Melody "Mellie" Grant is the First Lady of the United States of America. Her relationship with her husband, President Fitzgerald Grant, is constantly tested due to his infidelity and her betrayal of his trust on various different occasions.

Mellie is highly educated and eloquent. She often lets her emotional stresses affect her motives, however she has the ability to see the "bigger picture" and overcome her own problems for the purpose of the President and his administration.