While accused had been used as a verb in the past, Shakespeare was the first one to popularize it as a noun. Example: The accused will defend himself tomorrow.
This adjective means that good fortune or success should follow. It is thought that Shakespeare received his inspiration from a Roman practice of fortune telling by looking at the path a bird had flown (called an auspice).
Besmirch is first seen in I Henry IV. It is still used today and means to damage or hurt someone's name or reputation.
While the noun blanket had long been used, Shakespeare was the first to use it as a verb meaning: to cover.
This is another word which was used before as a noun, but Shakespeare coined as a verb. It was first seen in Timon of Athens.
Describing animals as cold-blooded was not Shakespeare's intent. Rather, in Kind John he first used to term to mean someone who was behaving in a heartless manner.
In an example of poetic license, Shakespeare was the first to use deafening to mean something that was very loud, yet did not actually make a person deaf. It was first seen in II Henry IV.
Shakespeare didn't mind borrowing from other languages. Domineering has been around in the Netherlands as a Dutch word, but Love's Labour's Lost was the first time it was used in the the English language.